Gene

rpe65c

ID
ZDB-GENE-081104-505
Name
retinoid isomerohydrolase RPE65 c
Symbol
rpe65c Nomenclature History
Previous Names
  • si:ch211-198n5.12 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Exhibits retinol isomerase activity. Predicted to be involved in retinoid metabolic process. Localizes to cytosol and membrane. Is expressed in Muller cell; retina; retinal ganglion cell layer; and retinal inner nuclear layer. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 2; retinitis pigmentosa; and retinitis pigmentosa 20. Orthologous to human RPE65 (retinoid isomerohydrolase RPE65).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rpe65c Human Ortholog
No data available
Associated With rpe65c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004294 Carotenoid oxygenase
Domain Details Per Protein
Protein Length Carotenoid oxygenase
UniProtKB:A9C3R8
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA rpe65c-201 (1) Havana 1661 nt
mRNA rpe65c-202 (1) Ensembl 906 nt
mRNA rpe65c-203 (1) Ensembl 1599 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-rpe65c polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations