Gene

lct

ID
ZDB-GENE-081104-434
Name
lactase
Symbol
lct Nomenclature History
Previous Names
  • si:dkey-79p17.2
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to be involved in carbohydrate metabolic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in congenital lactase deficiency. Orthologous to human LCT (lactase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lct Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital lactase deficiency Alliance Lactase deficiency, congenital 223000
Associated With lct Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018120 Glycoside hydrolase family 1, active site
Conserved_site IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site
Family IPR001360 Glycoside hydrolase family 1
Homologous_superfamily IPR017853 Glycoside hydrolase superfamily
Domain Details Per Protein
Protein Length Glycoside hydrolase family 1 Glycoside hydrolase family 1, active site Glycoside hydrolase superfamily Glycosyl hydrolases family 1, N-terminal conserved site
UniProtKB:F1Q8B5 1900
UniProtKB:A0A0G2KIT0 1898
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations