ZFIN ID: ZDB-GENE-081104-434
Gene Name: lactase
Gene Symbol: lct    Nomenclature History

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Previous Name: si:dkey-79p17.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to be involved in carbohydrate metabolic process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in congenital lactase deficiency. Orthologous to human LCT (lactase).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000060671 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2489 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH lct HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital lactase deficiency Alliance Lactase deficiency, congenital 223000
DISEASE ASSOCIATED WITH lct VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process carbohydrate metabolic process (more)
Cellular Component integral component of membrane (more)
Molecular Function hydrolase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lct-201 (1)    Ensembl 5703
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lct No data available
MARKER RELATIONSHIPS
lct Contained in: [BAC] DKEY-79P17 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
Genomic GenBank:CR394556 (1) 136863 nt
Select Tool
Polypeptide UniProtKB:F1Q8B5 (1) 1900 aa
Sequence Information (all 3)
ORTHOLOGY for lct ( Chr: 9 )
CITATIONS (11)