Gene

lzts1

ID
ZDB-GENE-081104-431
Name
leucine zipper, putative tumor suppressor 1
Symbol
lzts1 Nomenclature History
Previous Names
  • si:dkey-63d15.13
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have microtubule binding activity. Predicted to be involved in regulation of dendrite morphogenesis and regulation of synaptic plasticity. Predicted to localize to dendritic spine. Is expressed in female organism. Human ortholog(s) of this gene implicated in esophageal cancer and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lzts1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
esophageal cancer Alliance Esophageal squamous cell carcinoma, somatic 133239
Associated With lzts1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR033293 Leucine zipper putative tumour suppressor 1
Family IPR045329 Leucine zipper putative tumor suppressor
Domain Details Per Protein
Protein Length Leucine zipper putative tumor suppressor Leucine zipper putative tumour suppressor 1
UniProtKB:F1QXP6 712
UniProtKB:F1R558 323
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations