Gene

lzts1

ID
ZDB-GENE-081104-431
Name
leucine zipper, putative tumor suppressor 1
Symbol
lzts1 Nomenclature History
Previous Names
  • si:dkey-63d15.13
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have microtubule binding activity. Predicted to be involved in mitotic cell cycle phase transition. Human ortholog(s) of this gene implicated in esophageal cancer and squamous cell carcinoma. Is expressed in female organism. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lzts1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Esophageal squamous cell carcinoma, somatic 133239
Associated With lzts1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR045329 Leucine zipper putative tumor suppressor
Domain Details Per Protein
Protein Length Leucine zipper putative tumor suppressor
UniProtKB:A0A8M9QA69 539
UniProtKB:A0A8N7TFD8 712
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA lzts1-201 (1) Ensembl 5543 nt
mRNA lzts1-202 (1) Havana 968 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations