ZFIN ID: ZDB-GENE-081104-348
Gene Name: leiomodin 1a (smooth muscle)
Gene Symbol: lmod1a    Nomenclature History

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Previous Names: lmod1, si:dkey-193l3.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Predicted to localize to striated muscle thin filament. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human LMOD1 (leiomodin 1).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000056111 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa127 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17930 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41229 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lmod1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lmod1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process muscle contraction (more)
    Cellular Component cytoskeleton (more)
    Molecular Function tropomyosin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lmod1a-201 (1)    Ensembl 2610
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lmod1a No data available
    MARKER RELATIONSHIPS
    lmod1a Contained in: [BAC] DKEY-193L3 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    Genomic GenBank:BX664742 (1) 215608 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q5S5 (1) 645 aa
    ORTHOLOGY for lmod1a ( Chr: 8 )
    CITATIONS (15)