Gene
adrb3b
- ID
- ZDB-GENE-081022-154
- Name
- adrenoceptor beta 3b
- Symbol
- adrb3b Nomenclature History
- Previous Names
-
- zgc:194843
- zgc:194852
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have beta3-adrenergic receptor activity; epinephrine binding activity; and norepinephrine binding activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure. Predicted to localize to integral component of plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; non-alcoholic fatty liver disease; and obesity. Orthologous to human ADRB3 (adrenoceptor beta 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wang et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
{Obesity, susceptibility to} | 601665 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
---|---|---|---|
UniProtKB:B3DIE4
|
405 | ||
UniProtKB:A0A8M9QKR9
|
417 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
adrb3b-201
(1)
|
Havana | 1676 nt |
Interactions and Pathways
No data available
Plasmids
No data available