Gene

adrb3b

ID
ZDB-GENE-081022-154
Name
adrenoceptor beta 3b
Symbol
adrb3b Nomenclature History
Previous Names
  • zgc:194843
  • zgc:194852
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have beta3-adrenergic receptor activity; epinephrine binding activity; and norepinephrine binding activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure. Predicted to localize to integral component of plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; non-alcoholic fatty liver disease; and obesity. Orthologous to human ADRB3 (adrenoceptor beta 3).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Wang et al., 2009
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Wang et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adrb3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
obesity Alliance {Obesity, susceptibility to} 601665
Associated With adrb3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:B3DIE4 405
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations