Gene

adrb1

ID
ZDB-GENE-081022-145
Name
adrenoceptor beta 1
Symbol
adrb1 Nomenclature History
Previous Names
  • zgc:194728
  • zgc:194731
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have beta1-adrenergic receptor activity. Involved in regulation of heart rate. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including adipose tissue; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypertension (multiple); low tension glaucoma; obstructive sleep apnea; and periodontitis. Orthologous to human ADRB1 (adrenoceptor beta 1).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adrb1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Resting heart rate] 607276
[Short sleep, familial natural, 2] 618591
Associated With adrb1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR002233 Adrenoceptor family
Domain Details Per Protein
Protein Length Adrenoceptor family GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:B3DHM6 390
UniProtKB:I7GPQ6 390
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations