ZFIN ID: ZDB-GENE-081022-123
Gene Name: zinc finger and BTB domain containing 24
Gene Symbol: zbtb24    Nomenclature History

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Previous Name: zgc:194556

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleoplasm. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 2. Orthologous to human ZBTB24 (zinc finger and BTB domain containing 24).
Genome Resources: Alliance (1),  Gene:553955 (1),  Ensembl(GRCz11):ENSDARG00000075533 (1)
GENE EXPRESSION
All Expression Data: Fig. 1 supplemental 2 from Rajshekar et al., 2018
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
mk19 Small Deletion Unknown Unknown TALEN
mk22 Indel Unknown Unknown TALEN
sa28797 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-zbtb24 N/A 1
TALEN1-zbtb24 1
TALEN2-zbtb24 1
TALEN3-zbtb24 1
DISEASE ASSOCIATED WITH zbtb24 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency-centromeric instability-facial anomalies syndrome 2 Alliance Immunodeficiency-centromeric instability-facial anomalies syndrome 2 614069
DISEASE ASSOCIATED WITH zbtb24 VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
immunodeficiency-centromeric instability-facial anomalies syndrome zbtb24mk22/mk22 standard conditions Rajshekar et al., 2018
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription by RNA polymerase II (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA zbtb24-201 (1)    Ensembl 4805
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM zbtb24 No data available
MARKER RELATIONSHIPS
zbtb24 Contained in: [BAC] CH73-242M19 (1)
zbtb24 Encodes: [cDNA] MGC:194556 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001023572 (1) 2019 nt
Genomic GenBank:CU469532 (1) 67813 nt
Select Tool
Polypeptide UniProtKB:A0A2R8QM31 (1) 695 aa
Sequence Information (all 15)
ORTHOLOGY for zbtb24 ( Chr: 17 )
CITATIONS (21)