Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-081003-1
Gene Name: wingless-type MMTV integration site family, member 3
Gene Symbol: wnt3
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 5 publications
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Larval:Day 6 (144.0h-168.0h)
  basal plate midbrain region, cerebellum, diencephalon, diencephalon central region (all 17) expand
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-wnt3 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Tetra-amelia, autosomal recessive 273395
GENE ONTOLOGY
Ontology GO Term
Biological Process thalamus development (more)
Cellular Component extracellular region (more)
Molecular Function receptor binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005817 (1)
  • InterPro:IPR009141 (1)
  • InterPro:IPR018161 (1)
  • PROSITE:PS00246 (1)
  • Pfam:PF00110 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000055996 (1) 1498
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt3
    Tg(hsp70l:wnt3-GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    wnt3 Contained in: [BAC] CH211-177M15 (1) (order this), DKEY-29B5 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001114552 (1) 1499 bp
    Genomic GenBank:CR388157 (1) 225145 bp Blast at MegaBLAST
    Polypeptide UniProtKB:B0LK22 (1) 355 aa
    Sequence Clusters UniGene:143523 (1)
    Sequence Information (all 14)
    OTHER wnt3 GENE PAGES
  • Gene:569420 (1)
  • VEGA:OTTDARG00000035654 (1)
  • Ensembl(Zv9):ENSDARG00000038990 (1)
  • MAPPING INFORMATION
    Chr: 12 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish wnt3 12  
    Human WNT3 17 (17q21)
  • OMIM:165330
  • Gene:7473
  • Mouse Wnt3 11 ( 67.50 cM)
  • MGI:98955
  • Gene:22415
  • CITATIONS (21)