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General Information
ZIRC
ZFIN ID: ZDB-GENE-081001-1
Gene Name: leptin a
Gene Symbol: lepa
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: lep, ob (1), si:dkey-98o11.2

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have hormone activity. Involved in camera-type eye development; inner ear development; and nervous system development. Predicted to localize to the extracellular region. Human  ...
GENE EXPRESSION
All Expression Data: 11 figures from 9 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cy50 Small Deletion Unknown Unknown TALEN
vu621 Small Deletion Unknown Unknown CRISPR
vu622 Small Deletion Unknown Unknown CRISPR
Targeting reagents:
DISEASE ASSOCIATED WITH lepa HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Obesity, morbid, due to leptin deficiency 614962
DISEASE ASSOCIATED WITH lepa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process camera-type eye development (more)
Cellular Component extracellular region (more)
Molecular Function hormone activity (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000065 (1)
  • InterPro:IPR009079 (1)
  • Pfam:PF02024 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lepa-201 (1) 501
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lepa No data available
    MARKER RELATIONSHIPS
    lepaContained in: [BAC] DKEY-98O11 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128576 (1)
    Genomic GenBank:BX927136 (1) 93818bp
    Select Tool
    Polypeptide UniProtKB:Q0D250 (1) 166aa
    Sequence Clusters UniGene:148389 (1)
    Sequence Information (all 11)
    ORTHOLOGY for lepa (Chr: 18)
    CITATIONS (54)