Gene

ca12

ID
ZDB-GENE-080815-4
Name
carbonic anhydrase XII
Symbol
ca12 Nomenclature History
Previous Names
  • si:dkeyp-73b11.11
  • zmp:0000000627
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to localize to plasma membrane. Is expressed in muscle. Human ortholog(s) of this gene implicated in isolated hyperchlorhidrosis. Orthologous to human CA12 (carbonic anhydrase 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Esbaugh et al., 2009
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ca12 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
isolated hyperchlorhidrosis Alliance Hyperchlorhidrosis, isolated 143860
Associated With ca12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018338 Carbonic anhydrase, alpha-class, conserved site
Domain IPR001148 Alpha carbonic anhydrase domain
Family IPR018430 Carbonic anhydrase, CA-XII
Family IPR023561 Carbonic anhydrase, alpha-class
Homologous_superfamily IPR036398 Alpha carbonic anhydrase domain superfamily
Domain Details Per Protein
Protein Length Alpha carbonic anhydrase domain Alpha carbonic anhydrase domain superfamily Carbonic anhydrase, alpha-class Carbonic anhydrase, alpha-class, conserved site Carbonic anhydrase, CA-XII
UniProtKB:X1WD95 257
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations