Gene

hspg2

ID
ZDB-GENE-080807-4
Name
heparan sulfate proteoglycan 2
Symbol
hspg2 Nomenclature History
Previous Names
  • perlecan (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity. Acts upstream of or within several processes, including blood vessel endothelial cell migration; embryonic viscerocranium morphogenesis; and endothelial cell proliferation. Predicted to be located in basement membrane and extracellular region. Is expressed in several structures, including axial vasculature; eye; immature eye; trunk; and trunk musculature. Human ortholog(s) of this gene implicated in Schwartz-Jampel syndrome 1; Silverman-Handmaker type dyssegmental dysplasia; and osteochondrodysplasia. Orthologous to human HSPG2 (heparan sulfate proteoglycan 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
19 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hspg2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Schwartz-Jampel syndrome 1 Alliance Schwartz-Jampel syndrome, type 1 255800
Silverman-Handmaker type dyssegmental dysplasia Alliance Dyssegmental dysplasia, Silverman-Handmaker type 224410
Associated With hspg2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-hspg2 polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations