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ZIRC
ZFIN ID: ZDB-GENE-080724-2
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Gene Name: cytoplasmic FMR1 interacting protein 2
Gene Symbol: cyfip2
Sequence Ontology ID : SO:0000704

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Previous Names: nev (1), nevermind (1), zgc:194528

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in retina layer formation; retinal ganglion cell axon guidance; and startle response. Predicted to localize to the neuron projection and synapse. Human ortholog(s) of this gene implicated in  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
p400 Point Mutation Unknown Unknown ENU
sa642 Point Mutation Unknown Splice Site ENU
sa1556 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa16828 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • ta229f Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • tr230b Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 18 figures from 6 publications
    Observed in:
    DISEASE ASSOCIATED WITH cyfip2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    early infantile epileptic encephalopathy 65 Epileptic encephalopathy, early infantile, 65 618008
    DISEASE ASSOCIATED WITH cyfip2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process retina layer formation (more)
    Cellular Component cytoplasm (more)
    Molecular Function NOT RNA 7-methylguanosine cap binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR008081 (1)
  • InterPro:IPR009828 (1)
    		•
  • Pfam:PF05994 (1)
  • Pfam:PF07159 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyfip2-201 (1) 4023
    Select Tool
    cyfip2-202 (1) 5369
    Select Tool
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cyfip2
    MARKER RELATIONSHIPS
    cyfip2Contained in: [BAC] CH73-22O18 (1) (order this), CH73-127I13 (1) (order this)
    cyfip2Encodes: [cDNA] MGC:194528 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001097587 (1) 4023bp
    Select Tool
    Genomic GenBank:FP016207 (1) 126002bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8PX02 (1) 1254aa
    Select Tool
    Sequence Clusters UniGene:83830 (1)
    Sequence Information (all 20)
    OTHER cyfip2 GENE PAGES
  • Alliance (1)
  • Gene:100002872 (1)
  • VEGA:OTTDARG00000032112 (1)
  • Ensembl(GRCz11):ENSDARG00000036375 (1)
    • ORTHOLOGY for cyfip2 (Chr: 14)
    CITATIONS (28)