Gene

skilb

ID
ZDB-GENE-080723-40
Name
SKI-like proto-oncogene b
Symbol
skilb Nomenclature History
Previous Names
  • zgc:193698
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Predicted to be involved in negative regulation of BMP signaling pathway; negative regulation of transcription by RNA polymerase II; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human SKIL (SKI like proto-oncogene).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With skilb Human Ortholog
No data available
Associated With skilb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003380 SKI/SNO/DAC domain
Domain IPR014890 c-SKI SMAD4-binding domain
Family IPR023216 Transcription regulator SKI/SnoN
Family IPR028373 Ski-related oncogene Sno
Homologous_superfamily IPR009061 Putative DNA-binding domain superfamily
Homologous_superfamily IPR010919 SAND-like domain superfamily
Homologous_superfamily IPR037000 Ski-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length c-SKI SMAD4-binding domain Putative DNA-binding domain superfamily SAND-like domain superfamily Ski-like, DNA-binding domain superfamily Ski-related oncogene Sno SKI/SNO/DAC domain Transcription regulator SKI/SnoN
UniProtKB:E7FGJ1 624
UniProtKB:B3DGU8 629
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations