ZFIN ID: ZDB-GENE-080723-17
Gene Name: cyclin-dependent kinase 5, regulatory subunit 1a (p35)
Gene Symbol: cdk5r1a    Nomenclature History

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Previous Names: zgc:194104 (1), zgc:194109 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have cyclin-dependent protein serine/threonine kinase activator activity and kinase activity. Involved in intrahepatic bile duct development. Predicted to localize to protein kinase 5 complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1).
Genome Resources: Alliance (1),  Gene:568402 (1),  Ensembl(GRCz11):ENSDARG00000037916 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
lri58 Small Deletion Exon 1 Unknown TALEN
sa20068 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    TALEN1-cdk5r1a 1
    DISEASE ASSOCIATED WITH cdk5r1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cdk5r1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intrahepatic bile duct development (more)
    Cellular Component protein kinase 5 complex (more)
    Molecular Function cyclin-dependent protein serine/threonine kinase activator activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cdk5r1a-201 (1)    Ensembl 994
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdk5r1a No data available
    MARKER RELATIONSHIPS
    cdk5r1a Contained in: [BAC] CH211-250G22 (1)
    cdk5r1a Encodes: [cDNA] MGC:194104 (1), MGC:194109 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001128742 (1) 994 nt
    Genomic GenBank:BX890565 (1) 120394 nt
    Select Tool
    Polypeptide UniProtKB:B3DH98 (1) 306 aa
    Sequence Information (all 13)
    ORTHOLOGY for cdk5r1a ( Chr: 3 )
    CITATIONS (18)