ZFIN ID: ZDB-GENE-080611-1
Gene Name: insulin-like growth factor 3
Gene Symbol: igf3    Nomenclature History

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Previous Name: igf1b (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Exhibits insulin-like growth factor receptor binding activity. Involved in oocyte maturation and sperm capacitation. Predicted to localize to extracellular space. Is expressed in several structures, including gill; gonad; head; kidney; and skeletal muscle.
Genome Resources: Alliance (1),  Gene:561569 (1),  Ensembl(GRCz11):ENSDARG00000058058 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH igf3 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH igf3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oocyte maturation (more)
Cellular Component extracellular region (more)
Molecular Function insulin-like growth factor receptor binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA igf3-201 (1)    Ensembl 685
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab2-igf3 polyclonal Rabbit WB 1
Ab1-igf3 polyclonal Rabbit WB 1
AB3-igf3 polyclonal Rabbit IHC 2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM igf3
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(-4.3igf3:EGFP) igf3 EGFP Danio rerio 2 4
Tg(-4.3igf3:EGFP-Hsa.KRAS_G12V) igf3 EGFP Danio rerioHomo sapiens 2 4
MARKER RELATIONSHIPS
igf3 Contained in: [BAC] DKEYP-110G5 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001115050 (1) 617 nt
Genomic GenBank:CT025854 (1) 184858 nt
Select Tool
Polypeptide UniProtKB:F1QNT1 (1) 193 aa
Sequence Information (all 13)
ORTHOLOGY for igf3 ( Chr: 8 )
CITATIONS (61)