ZFIN ID: ZDB-GENE-080424-6
Gene Name: myosin IXAb
Gene Symbol: myo9ab    Nomenclature History

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Previous Names: myo9a2 (1), myo9al2, im:7155152

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; GTPase activator activity; and actin binding activity. Involved in axon extension and swimming behavior. Predicted to localize to several cellular components, including growth cone; myosin complex; and synapse. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome. Orthologous to human MYO9A (myosin IXA).
Genome Resources: Alliance (1),  Gene:562199 (1),  Ensembl(GRCz11):ENSDARG00000073843 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from O'Connor et al., 2016
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 4 (96.0h-120.0h)
 
PHENOTYPE
Data: Fig. 1 from O'Connor et al., 2019
Observed in:
DISEASE ASSOCIATED WITH myo9ab HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myasthenic syndrome, congenital, 24, presynaptic 618198
DISEASE ASSOCIATED WITH myo9ab VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process axon development (more)
Cellular Component cell junction (more)
Molecular Function actin binding (more)
GO Terms (all 22)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA myo9ab-203 (1)    Ensembl 7584
ncRNA myo9ab-002 (1) 497
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myo9ab No data available
MARKER RELATIONSHIPS
myo9ab Contained in: [Fosmid] CH1073-360M4 (1)
myo9ab Encodes: [EST] IMAGE:7155152 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_021470568 (1)
Genomic GenBank:CABZ01074930 (1) 57974 nt
Select Tool
Polypeptide UniProtKB:E7F3F0 (1) 2286 aa
Sequence Information (all 18)
ORTHOLOGY for myo9ab ( Chr: 25 )
CITATIONS (24)