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ZIRC
ZFIN ID: ZDB-GENE-080424-6
Gene Name: myosin IXAb
Gene Symbol: myo9ab    Nomenclature History

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Previous Names: myo9a2 (1), myo9al2, im:7155152

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; GTPase activator activity; and actin binding activity. Involved in axon extension and swimming behavior. Predicted to localize to several cellular components, including the cell junction; growth cone; and myosin complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome. Orthologous to human MYO9A (myosin IXA).
Genome Resources: Alliance (1),  Gene:562199 (1),  Ensembl(GRCz11):ENSDARG00000073843 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from O'Connor et al., 2016
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16393 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24581 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30171 Point Mutation Unknown Premature Stop ENU
    sa37972 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39467 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44210 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-myo9ab N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH myo9ab HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Myasthenic syndrome, congenital, 24, presynaptic 618198
    DISEASE ASSOCIATED WITH myo9ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon development (more)
    Cellular Component cell junction (more)
    Molecular Function actin binding (more)
    GO Terms (all 21)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA myo9ab-203 (1)    Ensembl 7584
    ncRNA myo9ab-002 (1) 497
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM myo9ab No data available
    MARKER RELATIONSHIPS
    myo9ab Contained in: [Fosmid] CH1073-360M4 (1) (order this)
    myo9ab Encodes: [EST] IMAGE:7155152 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021470568 (1)
    Genomic GenBank:CABZ01074930 (1) 57974 bp
    Select Tool
    Polypeptide UniProtKB:E7F3F0 (1) 2286 aa
    Sequence Clusters UniGene:152214 (1)
    Sequence Information (all 19)
    ORTHOLOGY for myo9ab ( Chr: 25 )
    CITATIONS (21)