header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-080424-6
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: myosin IXAb
Gene Symbol: myo9ab    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: myo9a2 (1), myo9al2, im:7155152

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; GTPase activator activity; and actin binding activity. Involved in axon extension and swimming behavior. Predicted to localize to several cellular components, including the cell junction; growth cone; and myosin complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome. Orthologous to human MYO9A (myosin IXA).
Genome Resources: Alliance (1),  Gene:562199 (1),  Ensembl(GRCz11):ENSDARG00000073843 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from O'Connor et al., 2016
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16393 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24581 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa30171 Point Mutation Unknown Premature Stop ENU
    sa37972 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa39467 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa44210 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-myo9ab N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH myo9ab HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Myasthenic syndrome, congenital, 24, presynaptic 618198
    DISEASE ASSOCIATED WITH myo9ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon development (more)
    Cellular Component cell junction (more)
    Molecular Function actin binding (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000048 (1)
  • InterPro:IPR000159 (1)
  • InterPro:IPR000198 (1)
  • InterPro:IPR001609 (1)
  • InterPro:IPR002219 (1)
  • InterPro:IPR008936 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR028558 (1)
  • InterPro:IPR029071 (1)
  • InterPro:IPR036961 (1)
  • PROSITE:PS00479 (1)
  • PROSITE:PS50081 (1)
  • PROSITE:PS50096 (1)
  • PROSITE:PS50200 (1)
  • PROSITE:PS50238 (1)
  • PROSITE:PS51456 (1)
  • Pfam:PF00063 (1)
  • Pfam:PF00612 (1)
  • Pfam:PF00620 (1)
  • Pfam:PF00788 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA myo9ab-203 (1)    Ensembl 7584
    Select Tool
    ncRNA myo9ab-002 (1) 497
    Select Tool
    Browsers: NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM myo9ab No data available
    MARKER RELATIONSHIPS
    myo9ab Contained in: [Fosmid] CH1073-360M4 (1) (order this)
    myo9ab Encodes: [EST] IMAGE:7155152 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021470568 (1)
    Select Tool
    Genomic GenBank:CABZ01074930 (1) 57974 bp
    Select Tool
    Polypeptide UniProtKB:E7F3F0 (1) 2286 aa
    Select Tool
    Sequence Clusters UniGene:152214 (1)
    Sequence Information (all 19)
    ORTHOLOGY for myo9ab ( Chr: 25 )
    CITATIONS (21)