ZFIN ID: ZDB-GENE-080424-6 |
Gene Name: | myosin IXAb | ||||||
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Gene Symbol: | myo9ab Nomenclature History | ||||||
Previous Names: | myo9a2 (1), myo9al2, im:7155152 | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 25 Mapping Details/Browsers | ||||||
Description: | Predicted to have several functions, including ATP binding activity; GTPase activator activity; and actin binding activity. Involved in axon extension and swimming behavior. Predicted to localize to several cellular components, including the cell junction; growth cone; and myosin complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome. Orthologous to human MYO9A (myosin IXA). | ||||||
Genome Resources: | Alliance (1), Gene:562199 (1), Ensembl(GRCz11):ENSDARG00000073843 (2) |
All Expression Data: | Fig. S2 from O'Connor et al., 2016 |
Wild-type Stages, Structures: | Hatching:Long-pec (48.0h-60.0h) to Larval:Day 4 (96.0h-120.0h) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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sa16393 | Point Mutation | Unknown | Premature Stop | ENU |
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sa24581 | Point Mutation | Unknown | Premature Stop | ENU |
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sa30171 | Point Mutation | Unknown | Premature Stop | ENU | |
sa37972 | Point Mutation | Unknown | Premature Stop | ENU |
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sa39467 | Point Mutation | Unknown | Premature Stop | ENU |
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sa44210 | Point Mutation | Unknown | Splice Site | ENU |
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Targeting Reagent | Created Alleles | Publications |
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MO1-myo9ab | N/A | 2 |
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
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Myasthenic syndrome, congenital, 24, presynaptic | 618198 |
Ontology | GO Term |
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Biological Process | axon development (more) |
Cellular Component | cell junction (more) |
Molecular Function | actin binding (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
myo9ab-203
(1)
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7584 |
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ncRNA | myo9ab-002 (1) | 497 |
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Browsers: NCBI, Ensembl, ZFIN |
myo9ab Contained in: | [Fosmid] CH1073-360M4 (1) (order this) |
myo9ab Encodes: | [EST] IMAGE:7155152 (1) (order this) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:XM_021470568 (1) |
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Genomic | GenBank:CABZ01074930 (1) | 57974 bp | |
Polypeptide | UniProtKB:E7F3F0 (1) | 2286 aa |
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Sequence Clusters | UniGene:152214 (1) |