Gene

nlk2

ID
ZDB-GENE-080320-1
Name
nemo-like kinase, type 2
Symbol
nlk2 Nomenclature History
Previous Names
  • nlka
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have ATP binding activity and MAP kinase activity. Involved in midbrain development; peptidyl-threonine phosphorylation; and positive regulation of Wnt signaling pathway. Predicted to localize to cytoplasm and nucleus. Is expressed in head and midbrain. Orthologous to human NLK (nemo like kinase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Ota et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Ota et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nlk2 Human Ortholog
No data available
Associated With nlk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Conserved_site IPR003527 Mitogen-activated protein (MAP) kinase, conserved site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Mitogen-activated protein (MAP) kinase, conserved site Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:E7F1L8 533
UniProtKB:A9ZMG5 457
UniProtKB:B3IWJ8 452
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-nlk polyclonal Rabbit
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations