ZFIN ID: ZDB-GENE-080303-21
Gene Name: immunoglobulin superfamily member 11
Gene Symbol: igsf11    Nomenclature History

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Previous Names: seu, sc:d812

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Involved in late stripe melanocyte differentiation and melanocyte migration. Predicted to localize to integral component of membrane. Is expressed in several structures, including eye; gonad; heart; integument; and vertical myoseptum. Orthologous to human IGSF11 (immunoglobulin superfamily member 11).
Genome Resources: Alliance (1),  Gene:100004469 (1),  Ensembl(GRCz11):ENSDARG00000109783 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2008 [cssl:d812]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1863 Point Mutation Unknown Splice Site ENU
sa19127 Point Mutation Unknown Splice Site ENU
sa42630 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • utr15e1 Point Mutation Unknown Missense
    wp15e1 Point Mutation Unknown Missense ENU
    wp15e3 Point Mutation Unknown Missense ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-igsf11 N/A 1
    DISEASE ASSOCIATED WITH igsf11 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH igsf11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process late stripe melanocyte differentiation (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-igsf11 polyclonal Mouse IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM igsf11
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(mitfa:igsf11) mitfa igsf11 Danio rerio 1 3
    MARKER RELATIONSHIPS
    igsf11 Encodes: [cDNA] cssl:d812 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001278822 (1)
    Genomic GenBank:CR735141 (1) 108767 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8RYG1 (1) 442 aa
    Sequence Information (all 31)
    ORTHOLOGY for igsf11 ( Chr: 15 )
    CITATIONS (20)