ZFIN ID: ZDB-GENE-080220-22
Gene Name: acyl-CoA synthetase medium chain family member 3
Gene Symbol: acsm3    Nomenclature History

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Previous Name: zgc:172040

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have acyl-CoA ligase activity; fatty acid ligase activity; and fatty-acyl-CoA synthase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Predicted to localize to mitochondrial matrix. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to several human genes including ACSM3 (acyl-CoA synthetase medium chain family member 3).
Genome Resources: Alliance (1),  Gene:100002035 (1),  Ensembl(GRCz11):ENSDARG00000004880 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9805 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11987 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acsm3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {?Hypertension, essential}
    DISEASE ASSOCIATED WITH acsm3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process acyl-CoA metabolic process (more)
    Cellular Component mitochondrial matrix (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acsm3-201 (1)    Ensembl 3790
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acsm3 No data available
    MARKER RELATIONSHIPS
    acsm3 Contained in: [BAC] CH73-60L17 (1)
    acsm3 Encodes: [cDNA] MGC:172040 (1), MGC:198271 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001111236 (1) 3820 nt
    Genomic GenBank:CU467875 (1) 97856 nt
    Select Tool
    Polypeptide UniProtKB:A9JRA7 (1) 591 aa
    Sequence Information (all 15)
    ORTHOLOGY for acsm3 ( Chr: 2 )
    CITATIONS (16)