Gene

acsm3

ID

ZDB-GENE-080220-22

Name

acyl-CoA synthetase medium chain family member 3

Symbol

acsm3 Nomenclature History

Previous Names

zgc:172040

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable fatty acid ligase activity and fatty-acyl-CoA synthase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to several human genes including ACSM3 (acyl-CoA synthetase medium chain family member 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With acsm3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{?Hypertension, essential}

Associated With acsm3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020845	AMP-binding, conserved site
Domain	IPR000873	AMP-dependent synthetase/ligase domain
Domain	IPR025110	AMP-binding enzyme, C-terminal domain
Family	IPR051087	Mitochondrial Acyl-CoA Synthetase Medium-Chain
Homologous_superfamily	IPR042099	ANL, N-terminal domain
Homologous_superfamily	IPR045851	AMP-binding enzyme, C-terminal domain superfamily