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ZIRC
ZFIN ID: ZDB-GENE-080213-10
Gene Name: zgc:174259
Gene Symbol: zgc:174259    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1).
Genome Resources: Alliance (1),  Gene:791587 (1),  Ensembl(GRCz11):ENSDARG00000091136 (1)

Nomenclature Note: This gene is characterized by full length cDNAs isolated as part of the Zebrafish Gene Collection (ZGC). When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix `zgc:' indicates that this gene is represented by cDNAs generated by the ZGC project.

GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH zgc:174259 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH zgc:174259 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of endopeptidase activity (more)
Cellular Component extracellular space (more)
Molecular Function serine-type endopeptidase inhibitor activity (more)
GO Terms (all 3)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA zgc:174259-202 (1)    Ensembl 1505
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM zgc:174259 No data available
MARKER RELATIONSHIPS
zgc:174259 Contained in: [BAC] CH211-186E20 (1) (order this)
zgc:174259 Encodes: [cDNA] MGC:174259 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001111208 (1) 1509 bp
Genomic GenBank:CR559930 (1) 151158 bp
Select Tool
Polypeptide UniProtKB:A0A2R8PVM3 (1) 409 aa
Sequence Clusters UniGene:22139 (1)
Sequence Information (all 14)
ORTHOLOGY for zgc:174259 ( Chr: 5 )
CITATIONS (14)