Gene
focad
- ID
- ZDB-GENE-080213-1
- Name
- focadhesin
- Symbol
- focad Nomenclature History
- Previous Names
-
- gb:ct717615
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within regulation of post-transcriptional gene silencing. Predicted to be located in cytosol and focal adhesion. Is expressed in male organism. Used to study liver cirrhosis. Orthologous to human FOCAD (focadhesin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Moreno Traspas et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Moreno Traspas et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Liver disease, severe congenital | 619991 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| liver cirrhosis | focadimb6/imb6 (AB) | standard conditions | Moreno Traspas et al., 2022 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Armadillo-type fold | Focadhesin, C-terminal domain | Focadhesin/RST1 | Focadhesin/RST, DUF3730 |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AU35 | InterPro | 1806 | ||||
| UniProtKB:A0AB13A9W3 | InterPro | 1806 | ||||
| UniProtKB:E7FGT5 | InterPro | 1806 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
focad-201
(1)
|
Ensembl | 5,811 nt | ||
| ncRNA |
ottdart00000063356
(1)
|
Ensembl | 544 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance