ZFIN ID: ZDB-GENE-080204-52
Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Gene Symbol: abcb4
Sequence Ontology ID : SO:0000704

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Previous Names: abcb1b (1), zgc:172149

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  head, intestinal bulb, intestine, liver (all 5) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9671 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16234 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa25016 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-abcb4 (1), MO2-abcb4 (1)
    PHENOTYPE
    Data: 2 figures from Fischer et al., 2013
    Observed in: efflux transmembrane transporter activity
    DISEASE ASSOCIATED WITH abcb4 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cholecystitis Gallbladder disease 1 600803
    inflammatory bowel disease 13 {Inflammatory bowel disease 13} 612244
    intrahepatic cholestasis Cholestasis, intrahepatic, of pregnancy, 3 614972
    Cholestasis, progressive familial intrahepatic 3 602347
    {Colchicine resistance} 120080
    {Colchicine resistance} 120080
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to toxic substance (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATPase-coupled protein transmembrane transporter activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003439
  • InterPro:IPR003593
  • InterPro:IPR011527
  • InterPro:IPR017871
  • InterPro:IPR027417
  • PROSITE:PS00211
  • PROSITE:PS50893
  • PROSITE:PS50929
  • Pfam:PF00005
  • Pfam:PF00664
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abcb4-001 (1) 4032
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM abcb4 No data available
    MARKER RELATIONSHIPS
    abcb4Contained in: [BAC] CH211-215G1 (1) (order this), DKEY-24I24 (1) (order this)
    abcb4Encodes: [cDNA] MGC:172149 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001316714 (1) 4535bp
    Genomic GenBank:BX322614 (1) 199783bp
    Select Tool
    Polypeptide UniProtKB:E7F1E3 1275aa
    Sequence Clusters UniGene:110810 (1)
    Sequence Information (all 22)
    OTHER abcb4 GENE PAGES
  • Gene:100136865 (1)
  • VEGA:OTTDARG00000034201 (1)
  • Ensembl(GRCz10):ENSDARG00000010936 (1)
  • ORTHOLOGY for abcb4 (Chr: 16)
    CITATIONS (29)