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ZIRC
ZFIN ID: ZDB-GENE-080107-2
Gene Name: LIF receptor subunit alpha b
Gene Symbol: lifrb    Nomenclature History

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Previous Name: si:dkey-120e24.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to localize to the external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in osteochondrodysplasia. Is expressed in several structures, including immune system; liver; nervous system; notochord; and otic vesicle. Orthologous to human LIFR (LIF receptor subunit alpha).
Genome Resources: Alliance (1),  Gene:565104 (1),  Ensembl(GRCz11):ENSDARG00000039863 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6671 Point Mutation Unknown Premature Stop ENU
sa17514 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29572 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lifrb N/A 2
    DISEASE ASSOCIATED WITH lifrb HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Stuve-Wiedemann syndrome/Schwartz-Jampel type 2 syndrome 601559
    DISEASE ASSOCIATED WITH lifrb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    Molecular Function cytokine receptor activity (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lifrb-202 (1)    Ensembl 3101
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lifrb No data available
    MARKER RELATIONSHIPS
    lifrb Contained in: [BAC] DKEY-120E24 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113732 (1)
    Genomic GenBank:CT827810 (1) 97913 bp
    Select Tool
    Polypeptide UniProtKB:F1Q5F5 (1) 960 aa
    Sequence Clusters UniGene:90352 (1)
    Sequence Information (all 13)
    ORTHOLOGY for lifrb ( Chr: 21 )
    CITATIONS (20)