ZFIN ID: ZDB-GENE-080104-1
Gene Name: leptin receptor
Gene Symbol: lepr
Sequence Ontology ID : SO:0000704

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Previous Name: obr (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
GENE EXPRESSION
All Expression Data: 17 figures from 8 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb251 Indel Exon 8 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • ihb252 Small Deletion Exon 8 Unknown CRISPR
    la025495Tg Transgenic Insertion Unknown Unknown DNA
    sa323 Point Mutation Unknown Premature Stop ENU
    sa1508 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa5372 Point Mutation Unknown Premature Stop ENU
    sa12953 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38556 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 8 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH lepr HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Obesity, morbid, due to leptin receptor deficiency 614963
    DISEASE ASSOCIATED WITH lepr VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process camera-type eye development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function leptin receptor activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003961 (1)
  • InterPro:IPR010457 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR015752 (1)
  • InterPro:IPR036116 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF06328 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lepr-001 (1) 5772
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lepr
    MARKER RELATIONSHIPS
    leprContained in: [BAC] CH211-157E20 (order this), DKEY-1K24 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113376 (1) 3342bp
    Genomic GenBank:BX936440 (1) 197744bp
    Select Tool
    Polypeptide UniProtKB:A8WH80 (1) 1091aa
    Sequence Clusters UniGene:93001 (1)
    Sequence Information (all 22)
    OTHER lepr GENE PAGES
  • Alliance (1)
  • Gene:567241 (1)
  • VEGA:OTTDARG00000026817 (1)
  • ORTHOLOGY for lepr (Chr: 6)
    CITATIONS (46)