ZFIN ID: ZDB-GENE-080103-2
Gene Name: prolactin receptor a
Gene Symbol: prlra
Sequence Ontology ID : SO:0000704

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Previous Name: wu:fj65c07

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine binding activity, peptide hormone binding activity, and prolactin receptor activity; predicted to be involved in prolactin signaling pathway; predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43590 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44958 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE
    Data: Fig. 4 from Liu et al., 2006
    Observed in:
    DISEASE ASSOCIATED WITH prlra HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Multiple fibroadenomas of the breast 615554
    Hyperprolactinemia 615555
    Hyperprolactinemia 615555
    DISEASE ASSOCIATED WITH prlra VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process prolactin signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cytokine receptor activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003528 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR015152 (1)
  • InterPro:IPR033230 (1)
  • InterPro:IPR036116 (1)
  • PROSITE:PS01352 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF09067 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA prlra-201 (1) 6237
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM prlra No data available
    MARKER RELATIONSHIPS
    prlraContained in: [BAC] CH211-213L7 (1) (order this), DKEY-264M23 (order this)
    prlraEncodes: [EST] fj65c07
    [cDNA] MGC:194467 (1) (order this), MGC:194475 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128677 (1)
    Genomic GenBank:CR318662 (1) 200648bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QG81 (1) 606aa
    Sequence Clusters UniGene:80289 (1)
    Sequence Information (all 29)
    OTHER prlra GENE PAGES
  • Alliance (1)
  • Gene:407651 (1)
  • VEGA:OTTDARG00000031317 (1)
  • Ensembl(GRCz11):ENSDARG00000016570 (2)
  • ORTHOLOGY for prlra (Chr: 21)
    CITATIONS (26)