ZFIN ID: ZDB-GENE-071126-1
Gene Name: leucine rich repeat neuronal 1
Gene Symbol: lrrn1    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Involved in olfactory nerve formation and olfactory placode morphogenesis. Predicted to localize to extracellular matrix and extracellular space. Is expressed in basal plate midbrain region; hindbrain neural keel; nervous system; neural plate; and somite. Orthologous to human LRRN1 (leucine rich repeat neuronal 1).
Genome Resources: Alliance (1),  Gene:568527 (1),  Ensembl(GRCz11):ENSDARG00000060115 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh283 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hu3284 Point Mutation Unknown Missense ENU
    hu3586 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ihb121 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb122 Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • lrrn1_unrecovered Point Mutation Unknown Unknown ENU
    sa18488 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33942 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-lrrn1 1
    MO1-lrrn1 N/A 1
    DISEASE ASSOCIATED WITH lrrn1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lrrn1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process olfactory nerve formation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lrrn1-201 (1)    Ensembl 3497
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-lrrn1 monoclonal IgG1 , k Mouse 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lrrn1 No data available
    MARKER RELATIONSHIPS
    lrrn1 Contained in: [BAC] DKEY-178O16 (1) (order this)
    lrrn1 Encodes: [EST] IMAGE:7159467 (1), IMAGE:7160133 (1)
    [cDNA] MGC:172337 (1)
    lrrn1 Has Artifact: [EST] fc41b03
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001130694 (1) 3529 nt
    Genomic GenBank:CU468905 (1) 271044 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A9JRH0 (1) 717 aa
    Sequence Information (all 17)
    ORTHOLOGY for lrrn1 ( Chr: 6 )
    CITATIONS (35)