ZFIN ID: ZDB-GENE-071120-8
Gene Name: interferon gamma receptor 1-like
Gene Symbol: ifngr1l    Nomenclature History

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Previous Names: crfb13, ifngr1-1, IFNGR1-1 (1), si:ch211-165e15.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in asthma; hepatitis B; primary immunodeficiency disease; and tuberculosis. Is expressed in brain; cardiovascular system; gill; muscle; and pleuroperitoneal region. Orthologous to human IFNGR1 (interferon gamma receptor 1).
Genome Resources: Alliance (1),  Gene:100329124 (1),  Ensembl(GRCz11):ENSDARG00000074488 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018387Tg Transgenic Insertion Unknown Unknown DNA
sa35395 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ifngr1l N/A 2
    MO2-ifngr1l N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ifngr1l HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Immunodeficiency 27A, mycobacteriosis, AR 209950
    Immunodeficiency 27B, mycobacteriosis, AD 615978
    {H. pylori infection, susceptibility to} 600263
    {Hepatitis B virus infection, susceptibility to} 610424
    {Tuberculosis infection, protection against} 607948
    {Tuberculosis, susceptibility to} 607948
    DISEASE ASSOCIATED WITH ifngr1l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cytokine-mediated signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cytokine receptor activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ifngr1l-202 (1)    Ensembl 517
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ifngr1l No data available
    MARKER RELATIONSHIPS
    ifngr1l Contained in: [BAC] CH73-52P7 (1), CH211-165E15 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001171592 (1)
    Genomic GenBank:BX004843 (1) 131026 nt
    Select Tool
    Polypeptide UniProtKB:D2JGP1 (1) 385 aa
    Sequence Information (all 12)
    ORTHOLOGY for ifngr1l ( Chr: 13 )
    CITATIONS (25)