Gene

ddx6

ID
ZDB-GENE-070912-83
Name
DEAD (Asp-Glu-Ala-Asp) box helicase 6
Symbol
ddx6 Nomenclature History
Previous Names
  • p54a (1)
  • si:ch211-147p17.1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have mRNA binding activity. Involved in response to heat and stress granule assembly. Localizes to cytoplasmic ribonucleoprotein granule. Orthologous to human DDX6 (DEAD-box helicase 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zampedri et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ddx6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with impaired language and dysmorphic facies 618653
Associated With ddx6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
Domain IPR001650 Helicase, C-terminal domain-like
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR014014 RNA helicase, DEAD-box type, Q motif
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length ATP-dependent RNA helicase DEAD-box, conserved site DEAD/DEAH box helicase domain Helicase, C-terminal domain-like Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase RNA helicase, DEAD-box type, Q motif
UniProtKB:E7FD91 484
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA ddx6-201 (1) Havana 5615 nt
mRNA ddx6-202 (1) Ensembl 6780 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-p54 Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations