ZFIN ID: ZDB-GENE-070912-423
Gene Name: retinitis pigmentosa GTPase regulator a
Gene Symbol: rpgra    Nomenclature History

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Previous Names: rpgr1 (1), rpgr, si:dkey-19h21.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Is expressed in several structures, including eye; gonad; muscle; neural tube; and optic cup. Human ortholog(s) of this gene implicated in X-linked cone-rod dystrophy 1; retinitis pigmentosa; and retinitis pigmentosa 3. Orthologous to human RPGR (retinitis pigmentosa GTPase regulator).
Genome Resources: Alliance (1),  Gene:571327 (1),  Ensembl(GRCz11):ENSDARG00000056617 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14986 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41448 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rpgra N/A 1
    MO2-rpgra N/A 1
    DISEASE ASSOCIATED WITH rpgra HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    retinitis pigmentosa 3 Alliance Retinitis pigmentosa 3 300029
    X-linked cone-rod dystrophy 1 Alliance Cone-rod dystrophy, X-linked, 1 304020
    Macular degeneration, X-linked atrophic 300834
    Retinitis pigmentosa, X-linked, and sinorespiratory infections, with or without deafness 300455
    DISEASE ASSOCIATED WITH rpgra VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY No data available
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rpgra-202 (1)    Ensembl 5081
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-rpgr polyclonal IgG Rabbit IHC Atlas Antibodies AB
    3
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rpgra No data available
    MARKER RELATIONSHIPS
    rpgra Contained in: [BAC] DKEY-19H21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001171588 (1)
    Genomic GenBank:BX571713 (1) 103882 nt
    Select Tool
    Polypeptide UniProtKB:F1QV77 (1) 1698 aa
    Sequence Information (all 10)
    ORTHOLOGY for rpgra ( Chr: 9 )
    CITATIONS (13)