ZFIN ID: ZDB-GENE-070912-197
Gene Name: adenylate cyclase 8 (brain)
Gene Symbol: adcy8    Nomenclature History

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Previous Names: ADCY_3 (1), si:ch211-220f13.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have adenylate cyclase activity. Involved in axon midline choice point recognition and retinal ganglion cell axon guidance. Predicted to localize to integral component of plasma membrane. Is expressed in retinal ganglion cell. Orthologous to human ADCY8 (adenylate cyclase 8).
Genome Resources: Alliance (1),  Gene:100148976 (1),  Ensembl(GRCz11):ENSDARG00000031783 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Xu et al., 2010
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
DISEASE ASSOCIATED WITH adcy8 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH adcy8 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process axon midline choice point recognition (more)
Cellular Component integral component of membrane (more)
Molecular Function adenylate cyclase activity (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA adcy8-202 (1)    Ensembl 2646
adcy8-203 (1)    Ensembl 937
adcy8-204 (1)    Ensembl 738
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM adcy8 No data available
MARKER RELATIONSHIPS
adcy8 Contained in: [BAC] CH211-220F13 (1), DKEY-178O23 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001143752 (1) 4155 nt
Genomic GenBank:BX005083 (1) 212081 nt Blast at MegaBLAST
Polypeptide UniProtKB:B7UCF8 (1) 1225 aa
Sequence Information (all 13)
ORTHOLOGY for adcy8 ( Chr: 2 )
CITATIONS (21)