ZFIN ID: ZDB-GENE-070911-3
Gene Name: splA/ryanodine receptor domain and SOCS box containing 4a
Gene Symbol: spsb4a    Nomenclature History

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Previous Names: spsb4 (1), ssb-4 (1), si:dkeyp-90g12.2, wu:fb38e11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to the SCF ubiquitin ligase complex. Is expressed in brain; head; and reproductive system. Orthologous to human SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4).
Genome Resources: Alliance (1),  Gene:557906 (1),  Ensembl(GRCz11):ENSDARG00000016084 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028816Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16701 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH spsb4a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH spsb4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteasome-mediated ubiquitin-dependent protein catabolic process (more)
    Cellular Component SCF ubiquitin ligase complex (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001496 SOCS box domain
    Domain IPR001870 B30.2/SPRY domain
    Domain IPR003877 SPRY domain
    Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA spsb4a-201 (1)    Ensembl 2346
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM spsb4a No data available
    MARKER RELATIONSHIPS
    spsb4a Contained in: [BAC] DKEYP-55C8 (1), DKEYP-90G12
    spsb4a Encodes: [EST] fb38e11
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001256642 (1)
    Genomic GenBank:BX322588 (1) 192641 nt
    Select Tool
    Polypeptide UniProtKB:B0S5W3 (1) 277 aa
    Sequence Information (all 16)
    ORTHOLOGY for spsb4a ( Chr: 2 )
    CITATIONS (21)