| ZFIN ID: ZDB-GENE-070705-554 |
| Gene Name: | apolipoprotein Bb, tandem duplicate 2 | |||||||||||||
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| Gene Symbol: | apobb.2 Nomenclature History |
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Attributions
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| Previous Names: | apobb2 (1), apobl, si:dkeyp-88f5.1 (1) | |||||||||||||
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| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 20 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have lipid transporter activity. Predicted to be involved in lipid transport. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Is expressed in liver and yolk syncytial layer. Orthologous to human APOB (apolipoprotein B). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:100330435 (1), Ensembl(GRCz11):ENSDARG00000075016 | |||||||||||||
| All Expression Data: | 5 figures from 2 publications |
| Wild-type Stages, Structures: | Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult) |
| Allele | Type | Localization | Consequence | Mutagen | Suppliers |
|---|---|---|---|---|---|
| sa6658 | Point Mutation | Unknown | Premature Stop | ENU | |
| sa17651 | Point Mutation | Unknown | Premature Stop | ENU |
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| sa23825 | Point Mutation | Unknown | Premature Stop | ENU |
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| sa37185 | Point Mutation | Unknown | Premature Stop | ENU |
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| sa43552 | Point Mutation | Unknown | Premature Stop | ENU |
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| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial hypobetalipoproteinemia 1 | Alliance | Hypobetalipoproteinemia | 615558 |
| Hypercholesterolemia, familial, 2 | 144010 |
| Ontology | GO Term |
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| Biological Process | lipid transport (more) |
| Molecular Function | lipid transporter activity (more) |
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| Type | Name | Length (nt) | Analysis | |
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| mRNA |
apobb.2-201
(1)
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8195 |
Select Tool
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| Browsers: NCBI, Ensembl, ZFIN |
| Addgene:PCRII apoBb.2 |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:XM_002665806 (1) | 8104 bp |
Select Tool
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| Genomic | GenBank:CR545462 (1) | 199482 bp | |
| Polypeptide | UniProtKB:A0A286YBH9 (1) | 2534 aa |
Select Tool
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| Sequence Clusters | UniGene:157377 (1) |
