ZFIN ID: ZDB-GENE-070705-554
Gene Name: apolipoprotein Bb, tandem duplicate 2
Gene Symbol: apobb.2    Nomenclature History

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Previous Names: apobb2 (1), apobl, si:dkeyp-88f5.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have lipid transporter activity. Predicted to be involved in lipid transport. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B).
Genome Resources: Alliance (1),  Gene:100330435 (1),  Ensembl(GRCz11):ENSDARG00000075016
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH apobb.2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial hypobetalipoproteinemia 1 Alliance Hypobetalipoproteinemia 615558
Hypercholesterolemia, familial, 2 144010
DISEASE ASSOCIATED WITH apobb.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process lipid transport (more)
Cellular Component low-density lipoprotein particle (more)
Molecular Function lipid transporter activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA apobb.2-201 (1)    Ensembl 8195
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM apobb.2 No data available
MARKER RELATIONSHIPS
apobb.2 Contained in: [BAC] DKEYP-88F5 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_002665806 (1) 8104 nt
Genomic GenBank:CR545462 (1) 199482 nt
Select Tool
Polypeptide UniProtKB:A0A286YBH9 (1) 2534 aa
Sequence Information (all 10)
ORTHOLOGY for apobb.2 ( Chr: 20 )
CITATIONS (17)