Gene

adcy1a

ID
ZDB-GENE-070705-302
Name
adenylate cyclase 1a
Symbol
adcy1a Nomenclature History
Previous Names
  • si:dkey-162m2.1
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have adenylate cyclase activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and cAMP biosynthetic process. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44. Orthologous to human ADCY1 (adenylate cyclase 1).
Genome Resources
Note
None
Expression
All Expression Data
Fig. S1 from Xu et al., 2010
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. S3 from Santos-Cortez et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adcy1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 44 Alliance ?Deafness, autosomal recessive 44 610154
Associated With adcy1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
Domain IPR009398 Adenylate cyclase, conserved domain
Domain IPR032628 Adenylate cyclase, N-terminal
Family IPR030672 Adenylate cyclase
Homologous_superfamily IPR029787 Nucleotide cyclase
Domain Details Per Protein
Protein Length Adenylate cyclase Adenylate cyclase, conserved domain Adenylate cyclase, N-terminal Adenylyl cyclase class-3/4/guanylyl cyclase Adenylyl cyclase class-4/guanylyl cyclase, conserved site Nucleotide cyclase
UniProtKB:A0A0R4IFQ3 605
UniProtKB:D1MIA2 1114
UniProtKB:F1QQH5 1114
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations