Gene

wdfy3

ID
ZDB-GENE-070705-153
Name
WD repeat and FYVE domain containing 3
Symbol
wdfy3 Nomenclature History
Previous Names
  • si:ch211-259k10.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Orthologous to human WDFY3 (WD repeat and FYVE domain containing 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wdfy3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary autosomal dominant microcephaly 18 Alliance ?Microcephaly 18, primary, autosomal dominant 617520
Associated With wdfy3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR000306 FYVE zinc finger
Domain IPR000409 BEACH domain
Domain IPR017455 Zinc finger, FYVE-related
Domain IPR017986 WD40-repeat-containing domain
Domain IPR023362 PH-BEACH domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Homologous_superfamily IPR036372 BEACH domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Armadillo-type fold BEACH domain BEACH domain superfamily Concanavalin A-like lectin/glucanase domain superfamily FYVE zinc finger PH-BEACH domain WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily Zinc finger, FYVE/PHD-type Zinc finger, FYVE-related Zinc finger, RING/FYVE/PHD-type
UniProtKB:A5PMK7 375
UniProtKB:A0A286Y869 3522
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations