ZFIN ID: ZDB-GENE-070702-1
Gene Name: lysosomal trafficking regulator
Gene Symbol: lyst
Previous Name: si:ch211-30i2.1
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION No data available
MUTANTS AND TARGETED KNOCKDOWNS

Allele Type Mutagen Suppliers
sa14050 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa14595 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17821 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Phenotype of Human Orthologue OMIM Phenotype ID
    Chediak-Higashi syndrome 214500
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lysosome organization (more)
    Cellular Component endomembrane system (more)
    Molecular Function phospholipid binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000409 (1)
  • InterPro:IPR001680 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR019775 (1)
  • InterPro:IPR023362 (1)
  • InterPro:IPR030464 (1)
  • PROSITE:PS00678 (1)
  • PROSITE:PS50082 (1)
  • PROSITE:PS50197 (1)
  • PROSITE:PS50294 (1)
  • Pfam:PF00400 (1)
  • Pfam:PF02138 (1)
  • Pfam:PF14844 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lyst-001 (1) 3815
    lyst-002 (1) 1565
    lyst-003 (1) 749
    lyst-004 (1) 1295
    lyst-005 (1) 2266
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lyst No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lyst Contained in: [BAC] CH73-258M18 (1) (order this), CH73-344P5 (1) (order this), CH211-30I2 (order this), CH211-93I23 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009307601 (1) 12456 bp
    Genomic GenBank:AL935031 178457 bp
    Select Tool
    Polypeptide UniProtKB:E9QFZ1 (1) 1862 aa
    Sequence Clusters UniGene:76146 (1)
    Sequence Information (all 20)
    OTHER lyst GENE PAGES
  • Gene:100150726 (1)
  • VEGA:OTTDARG00000029434 (1)
  • Ensembl(Zv9):ENSDARG00000008575 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish lyst 13  
    Human LYST 1 (1q42.1-q42.2)
  • OMIM:606897
  • Gene:1130
  • Orthology Details
    CITATIONS (10)