ZFIN ID: ZDB-GENE-070702-1
Gene Name: lysosomal trafficking regulator
Gene Symbol: lyst
Previous Name: si:ch211-30i2.1
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
muz107 Point Mutation Unknown Premature Stop ENU
sa14050 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14595 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa17821 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 3 figures from Kim et al., 2015
    Observed in: liver
    DISEASE ASSOCIATED WITH lyst HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Chediak-Higashi syndrome Chediak-Higashi syndrome 214500
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lysosome organization (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000409 (1)
  • InterPro:IPR001680 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR019775 (1)
  • InterPro:IPR023362 (1)
  • InterPro:IPR030464 (1)
  • PROSITE:PS00678 (1)
  • PROSITE:PS50082 (1)
  • PROSITE:PS50197 (1)
  • PROSITE:PS50294 (1)
  • Pfam:PF00400 (1)
  • Pfam:PF02138 (1)
  • Pfam:PF14844 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lyst-001 (1) 3815
    lyst-002 (1) 1565
    lyst-003 (1) 749
    lyst-004 (1) 1295
    lyst-005 (1) 2266
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lyst No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lystContained in: [BAC] CH73-258M18 (1) (order this), CH73-344P5 (1) (order this), CH211-30I2 (order this), CH211-93I23 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_017358861 (1) 12834bp
    Genomic GenBank:AL935031 178457bp
    Select Tool
    Polypeptide UniProtKB:E9QFZ1 (1) 2666aa
    Sequence Clusters UniGene:76146 (1)
    Sequence Information (all 20)
    OTHER lyst GENE PAGES
  • Gene:100150726 (1)
  • VEGA:OTTDARG00000029434 (1)
  • Ensembl(GRCz10):ENSDARG00000008575 (1)
  • ORTHOLOGY for lyst (Chr: 13)
    Species Symbol Chromosome Accession # Evidence
    Human LYST 1
  • Gene:1130
  • OMIM:606897
  • HGNC:1968
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (11)