ZFIN ID: ZDB-GENE-070702-1
Gene Name: lysosomal trafficking regulator
Gene Symbol: lyst
Previous Name: si:ch211-30i2.1
Location: Chr: 13   Details
Nomenclature History
GENE EXPRESSION No data available
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa14050, sa14595, sa17821
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Chediak-Higashi syndrome 214500
GENE ONTOLOGY
Ontology GO Term
Biological Process endosomal transport (more)
Cellular Component endomembrane system (more)
Molecular Function phospholipid binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000409 (1)
  • InterPro:IPR001680 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR019775 (1)
  • InterPro:IPR023362 (1)
  • PROSITE:PS00678 (1)
  • PROSITE:PS50082 (1)
  • PROSITE:PS50197 (1)
  • PROSITE:PS50294 (1)
  • Pfam:PF00400 (1)
  • Pfam:PF02138 (1)
  • Pfam:PF14844 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lyst-001 (1) 3815
    lyst-002 (1) 1565
    lyst-003 (1) 749
    lyst-004 (1) 1295
    lyst-005 (1) 2266
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lyst No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lyst Contained in: [BAC] CH73-258M18 (1) (order this), CH73-344P5 (1) (order this), CH211-30I2 (order this), CH211-93I23 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009307601 (1) 12456 bp
    Genomic GenBank:AL935031 178457 bp
    Select Tool
    Polypeptide UniProtKB:E9QFZ1 (1) 1862 aa
    Sequence Clusters UniGene:76146 (1)
    Sequence Information (all 20)
    OTHER lyst GENE PAGES
  • Gene:100150726 (1)
  • VEGA:OTTDARG00000029434 (1)
  • Ensembl(Zv9):ENSDARG00000008575 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish lyst 13  
    Human LYST 1 (1q42.1-q42.2)
  • OMIM:606897
  • Gene:1130
  • Orthology Details
    CITATIONS (9)