ZFIN ID: ZDB-GENE-070702-1
Gene Name: lysosomal trafficking regulator
Gene Symbol: lyst
Previous Name: si:ch211-30i2.1
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
muz107 Point Mutation ENU
sa14050 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa14595 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17821 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 3 figures from Kim et al., 2015
    Observed in: liver
    DISEASE ASSOCIATED WITH lyst HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Chediak-Higashi syndrome Chediak-Higashi syndrome 214500
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process lysosome organization (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000409 (1)
  • InterPro:IPR001680 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR019775 (1)
  • InterPro:IPR023362 (1)
  • InterPro:IPR030464 (1)
  • PROSITE:PS00678 (1)
  • PROSITE:PS50082 (1)
  • PROSITE:PS50197 (1)
  • PROSITE:PS50294 (1)
  • Pfam:PF02138 (1)
  • Pfam:PF14844 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lyst-001 (1) 3815
    lyst-002 (1) 1565
    lyst-003 (1) 749
    lyst-004 (1) 1295
    lyst-005 (1) 2266
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lyst No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    lystContained in: [BAC] CH73-258M18 (1) (order this), CH73-344P5 (1) (order this), CH211-30I2 (order this), CH211-93I23 (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009307601 (1) 12456bp
    Genomic GenBank:AL935031 178457bp
    Select Tool
    Polypeptide UniProtKB:E9QFZ1 (1) 2666aa
    Sequence Clusters UniGene:76146 (1)
    Sequence Information (all 20)
    OTHER lyst GENE PAGES 
  • Gene:100150726 (1)
  • VEGA:OTTDARG00000029434 (1)
  • Ensembl(GRCz10):ENSDARG00000008575 (1)
  • ORTHOLOGY for lyst (Chr: 13) 
    Species Symbol Chromosome Accession # Evidence
    Human LYST 1
  • Gene:1130
  • OMIM:606897
  • HGNC:1968
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (11)