Gene
ghrl
- ID
- ZDB-GENE-070622-2
- Name
- ghrelin/obestatin prepropeptide
- Symbol
- ghrl Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have growth hormone-releasing hormone activity. Involved in several processes, including chordate embryonic development; regulation of response to food; and response to food. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in diabetic neuropathy; morbid obesity; obesity; and type 2 diabetes mellitus. Is expressed in several structures, including diencephalon; digestive system; ghrelin secreting cell; heart; and pleuroperitoneal region. Orthologous to human GHRL (ghrelin and obestatin prepropeptide).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 44 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Motilin/ghrelin-associated peptide | Preproghrelin peptide |
|---|---|---|---|
|
UniProtKB:Q3ZV42
|
104 | ||
|
UniProtKB:F1QKX9
|
104 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-ghrl | monoclonal | Mouse |
|
Phoenix Pharmaceuticals, Inc.
|
1 |
Plasmids
No data available