ZFIN ID: ZDB-GENE-070615-28
Gene Name: G protein-coupled receptor 183a
Gene Symbol: gpr183a    Nomenclature History

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Previous Names: gpr183, ebi2, zgc:165579

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor activity and oxysterol binding activity. Involved in definitive hemopoiesis; endothelial to hematopoietic transition; and negative regulation of Notch signaling pathway. Predicted to localize to the plasma membrane. Is expressed in ventral wall of dorsal aorta. Orthologous to human GPR183 (G protein-coupled receptor 183).
Genome Resources: Alliance (1),  Gene:556770 (1),  Ensembl(GRCz11):ENSDARG00000010317 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ioz9 Small Deletion Exon 2 Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-gpr183a 1
CRISPR2-gpr183a
1
MO1-gpr183a N/A 1
DISEASE ASSOCIATED WITH gpr183a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH gpr183a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process endothelial to hematopoietic transition (more)
Cellular Component plasma membrane (more)
Molecular Function protein binding (more)
GO Terms (all 21)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gpr183a-201 (1)    Ensembl 1448
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gpr183a No data available
MARKER RELATIONSHIPS
gpr183a Contained in: [BAC] CH211-184M13 (1)
gpr183a Encodes: [cDNA] MGC:165579 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001099241 (1) 1466 nt
Genomic GenBank:BX470183 (1) 136116 nt
Select Tool
Polypeptide UniProtKB:A5PLE7 (1) 368 aa
Sequence Information (all 10)
ORTHOLOGY for gpr183a ( Chr: 9 )
CITATIONS (22)