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ZIRC
ZFIN ID: ZDB-GENE-070522-2
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Gene Name: nitric oxide synthase trafficking
Gene Symbol: nostrin    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Involved in several processes, including glomerular epithelium development; regulation of filopodium assembly; and sprouting angiogenesis. Orthologous to human NOSTRIN (nitric oxide synthase trafficking).
Genome Resources: Alliance (1),  Gene:100148449 (1),  Ensembl(GRCz11):ENSDARG00000077866 (1)
GENE EXPRESSION
All Expression Data: Fig. 1 from Kovacevic et al., 2012
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9638 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa15123 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa15830 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa25441 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-nostrin N/A 1
    MO2-nostrin N/A 1
    MO3-nostrin N/A 1
    MO4-nostrin N/A 1
    PHENOTYPE
    Data: 6 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH nostrin HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nostrin VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glomerular endothelium development (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001060 (1)
  • InterPro:IPR001452 (1)
  • InterPro:IPR027267 (1)
  • InterPro:IPR028535 (1)
  • InterPro:IPR031160 (1)
  • InterPro:IPR035656 (1)
  • InterPro:IPR036028 (1)
  • PROSITE:PS50002 (1)
  • PROSITE:PS51741 (1)
  • Pfam:PF00018 (1)
  • Pfam:PF00611 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nostrin-201 (1)    Ensembl 2682
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-nostrin polyclonal Rabbit WB 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nostrin No data available
    MARKER RELATIONSHIPS
    nostrin Contained in: [BAC] CH211-278B7 (order this)
    nostrin Encodes: [cDNA] MGC:171848 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113604 (1) 2599 bp
    Select Tool
    Genomic GenBank:CR626882 (1) 162906 bp
    Select Tool
    Polypeptide UniProtKB:A8WFV6 (1) 537 aa
    Select Tool
    Sequence Clusters UniGene:116535 (1)
    Sequence Information (all 13)
    ORTHOLOGY for nostrin ( Chr: 9 )
    CITATIONS (15)