ZFIN ID: ZDB-GENE-070501-8
Gene Name: collagen, type VI, alpha 3
Gene Symbol: col6a3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wu:fb06e12, wu:fs74g09

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase inhibitor activity. Involved in axon extension and motor neuron axon guidance. Predicted to localize to collagen-containing extracellular matrix and extracellular space. Is expressed in head. Human ortholog(s) of this gene implicated in Ullrich congenital muscular dystrophy; dystonia 27; and muscular dystrophy. Orthologous to human COL6A3 (collagen type VI alpha 3 chain).
Genome Resources: Alliance (1),  Gene:556874 (1),  Ensembl(GRCz11):ENSDARG00000077139 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Juvenile:Days 30-44 (30d-45d, 10 mm, adult fins/pigment)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa27398 Point Mutation Unknown Splice Site ENU
sa30917 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31713 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34639 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41416 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45357 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-col6a3 N/A 1
    MO2-col6a3 N/A 1
    MO3-col6a3 N/A 1
    MO4-col6a3 N/A 1
    DISEASE ASSOCIATED WITH col6a3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Bethlem myopathy Alliance Bethlem myopathy 1 158810
    dystonia 27 Alliance Dystonia 27 616411
    Ullrich congenital muscular dystrophy Alliance Ullrich congenital muscular dystrophy 1 254090
    DISEASE ASSOCIATED WITH col6a3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon extension (more)
    Cellular Component collagen-containing extracellular matrix (more)
    Molecular Function serine-type endopeptidase inhibitor activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA col6a3-203 (1)    Ensembl 914
    col6a3-205 (1)    Ensembl 11949
    col6a3-206 (1)    Ensembl 1209
    col6a3-207 (1)    Ensembl 2697
    ncRNA col6a3-003 (1)    Ensembl 849
    col6a3-005 (1)    Ensembl 894
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col6a3 No data available
    MARKER RELATIONSHIPS
    col6a3 Contained in: [BAC] DKEYP-74A11 (1)
    col6a3 Encodes: [EST] faa27f02, fb06e12, fs74g09
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NR_023329 (1)
    Genomic GenBank:CR545476 202562 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QKE8 (1) 3733 aa
    Sequence Information (all 42)
    ORTHOLOGY for col6a3 ( Chr: 9 )
    CITATIONS (22)