Gene

plod2

ID
ZDB-GENE-070326-1
Name
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Symbol
plod2 Nomenclature History
Previous Names
  • lh2 (1)
  • zgc:101868
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Exhibits procollagen-lysine 5-dioxygenase activity. Involved in several processes, including collagen biosynthetic process; collagen fibril organization; and skeletal muscle fiber development. Predicted to localize to endoplasmic reticulum. Is expressed in several structures, including fin; hypochord; intestine; shield; and skeletal system. Used to study Bruck syndrome. Orthologous to human PLOD2 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 2).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plod2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Bruck syndrome Alliance Bruck syndrome 2 609220
Associated With plod2 Via Experimental Models
Human Disease Fish Conditions Citations
Bruck syndrome plod2sa1768/sa1768 standard conditions (2)
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001006 Procollagen-lysine 5-dioxygenase, conserved site
Domain IPR005123 Oxoglutarate/iron-dependent dioxygenase
Domain IPR006620 Prolyl 4-hydroxylase, alpha subunit
Homologous_superfamily IPR029044 Nucleotide-diphospho-sugar transferases
Domain Details Per Protein
Protein Length Nucleotide-diphospho-sugar transferases Oxoglutarate/iron-dependent dioxygenase Procollagen-lysine 5-dioxygenase, conserved site Prolyl 4-hydroxylase, alpha subunit
UniProtKB:Q5U3N4 165
UniProtKB:B3DGT2 733
UniProtKB:A4U7F9 754
UniProtKB:A4U7F8 733
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-plod2 polyclonal IgG Rabbit
  • WB
Proteintech
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations