ZFIN ID: ZDB-GENE-070308-4
Gene Name: PDZ and LIM domain 2 (mystique)
Gene Symbol: pdlim2    Nomenclature History

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Previous Names: fi15c05, wu:fi15c05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have actin binding activity and muscle alpha-actinin binding activity. Predicted to be involved in actin cytoskeleton organization; heart development; and muscle structure development. Predicted to localize to Z disc; actin cytoskeleton; and adherens junction. Is expressed in aortic arch; digestive system; muscle; nervous system; and otic vesicle. Orthologous to human PDLIM2 (PDZ and LIM domain 2).
Genome Resources: Alliance (1),  Gene:560322 (1),  Ensembl(GRCz11):ENSDARG00000069956 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026541Tg Transgenic Insertion Unknown Unknown DNA
sa17842 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pdlim2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdlim2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pdlim2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin cytoskeleton organization (more)
    Cellular Component adherens junction (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pdlim2-201 (1)    Ensembl 2727
    pdlim2-202 (1)    Ensembl 713
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdlim2 No data available
    MARKER RELATIONSHIPS
    pdlim2 Contained in: [BAC] DKEY-206M7 (order this), DKEY-208C22 (1) (order this)
    pdlim2 Encodes: [EST] fi15c05
    [cDNA] MGC:163104 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001042766 (1) 2400 nt
    Genomic GenBank:CR855861 (1) 200837 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QCW0 (1) 364 aa
    Sequence Information (all 20)
    ORTHOLOGY for pdlim2 ( Chr: 8 )
    CITATIONS (25)