ZFIN ID: ZDB-GENE-070209-238
Gene Name: vascular cell adhesion molecule 1b
Gene Symbol: vcam1b    Nomenclature History

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Previous Names: vcam1, fi76d06, wu:fi76d06, zgc:158875 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Involved in lymphangiogenesis. Predicted to localize to integral component of membrane. Is expressed in several structures, including basal plate midbrain region; cardiovascular system; central nervous system; periderm; and trunk. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human VCAM1 (vascular cell adhesion molecule 1).
Genome Resources: Alliance (1),  Gene:561971 (1),  Ensembl(GRCz11):ENSDARG00000062479 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cas011 Small Deletion Exon 4 Unknown CRISPR
sa9939 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10702 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24124 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31070 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45764 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-vcam1b 1
    MO1-vcam1b N/A 1
    MO2-vcam1b N/A 1
    DISEASE ASSOCIATED WITH vcam1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vcam1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process lymphangiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vcam1b-201 (1)    Ensembl 3475
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vcam1b No data available
    MARKER RELATIONSHIPS
    vcam1b Contained in: [BAC] CH211-190N7 (1)
    vcam1b Encodes: [EST] fi76d06
    [cDNA] cssl:d127 (1), MGC:158875 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001083835 (1) 3460 nt
    Genomic GenBank:BX908733 (1) 153163 nt
    Select Tool
    Polypeptide UniProtKB:A2RV50 (1) 808 aa
    Sequence Information (all 21)
    ORTHOLOGY for vcam1b ( Chr: 22 )
    CITATIONS (24)