Gene

col11a1a

ID
ZDB-GENE-070209-167
Name
collagen, type XI, alpha 1a
Symbol
col11a1a Nomenclature History
Previous Names
  • col11a1
  • wu:fb34e11
  • wu:fc11b03
  • zgc:158335 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have extracellular matrix structural constituent. Predicted to localize to collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including cleithrum; cranial cartilage; ectoderm; hypochord; and trabecular layer. Human ortholog(s) of this gene implicated in Marshall syndrome; Stickler syndrome 2; autosomal dominant nonsyndromic deafness; and fibrochondrogenesis 1. Orthologous to human COL11A1 (collagen type XI alpha 1 chain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With col11a1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Deafness, autosomal dominant 37 618533
Fibrochondrogenesis 1 228520
Marshall syndrome 154780
Stickler syndrome, type II 604841
{Lumbar disc herniation, susceptibility to} 603932
Associated With col11a1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000885 Fibrillar collagen, C-terminal
Domain IPR001791 Laminin G domain
Domain IPR048287 Thrombospondin-like, N-terminal domain
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Repeat IPR008160 Collagen triple helix repeat
Domain Details Per Protein
Protein Length Collagen triple helix repeat Concanavalin A-like lectin/glucanase domain superfamily Fibrillar collagen, C-terminal Laminin G domain Thrombospondin-like, N-terminal domain
UniProtKB:A0A8M2B9X3 1715
UniProtKB:A2RUX5 1736
UniProtKB:A0A8M2B9U1 1785
UniProtKB:A0A8M2BA28 1814
UniProtKB:A0A8M9PXL6 1438
UniProtKB:A0A8M9PLW6 1686
UniProtKB:F1QSJ2 1813
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-col11a1a Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations