Gene

mavs

ID
ZDB-GENE-070112-1402
Name
mitochondrial antiviral signaling protein
Symbol
mavs Nomenclature History
Previous Names
  • wu:fj20d04
  • zgc:158392
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Exhibits protein heterodimerization activity. Involved in cytoplasmic pattern recognition receptor signaling pathway in response to virus; regulation of transcription, DNA-templated; and response to bacterium. Localizes to mitochondrion. Orthologous to human MAVS (mitochondrial antiviral signaling protein).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mavs Human Ortholog
No data available
Associated With mavs Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR031964 Caspase recruitment domain
Domain IPR042144 IPS1, CARD domain
Family IPR026148 Mitochondrial antiviral-signalling protein, metazoan
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length Caspase recruitment domain Death-like domain superfamily IPS1, CARD domain Mitochondrial antiviral-signalling protein, metazoan
UniProtKB:B8A4W5 219
UniProtKB:A1L1V0 348
UniProtKB:F1REK4 585
UniProtKB:C7C1L8 585
UniProtKB:B8A4W6 239
UniProtKB:B8A4W7 364
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations