Gene

atoh8

ID
ZDB-GENE-061215-7
Name
atonal bHLH transcription factor 8
Symbol
atoh8 Nomenclature History
Previous Names
  • Zath6 (1)
  • zgc:158314
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in animal organ morphogenesis; regulation of neural retina development; and regulation of skeletal muscle cell differentiation. Predicted to localize to nucleus. Is expressed in several structures, including nervous system; neural crest cell; optic cup; optic vesicle; and trunk. Orthologous to human ATOH8 (atonal bHLH transcription factor 8).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atoh8 Human Ortholog
No data available
Associated With atoh8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR032660 Protein atonal homologue 8
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Protein atonal homologue 8
UniProtKB:A1A5W5 181
UniProtKB:A0A2R8QKK1 269
UniProtKB:D2CLZ9 266
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations