ZFIN Gene: elna

ZFIN ID: ZDB-GENE-061212-1

ZFIN ID: ZDB-GENE-061212-1

Gene Name:

elastin a

Gene Symbol:

elna

Sequence Ontology ID :

SO:0000704

Previous Names:

eln1 (1), tropoelastin (1)

Location:

Chr: 15 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have extracellular matrix structural constituent. Predicted to localize to the elastic fiber. Human ortholog(s) of this gene implicated in several diseases, including aortic aneurysm ...

GENE EXPRESSION
All Expression Data:	11 figures from 3 publications
Wild-type Stages, Structures:	Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
	brain bulbus arteriosus cardiac ventricle cranium heart valve inner ear swim bladder ventral aorta ventricular system whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa11039	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa12235	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa17177	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa28377	Point Mutation	Unknown	Splice Site	ENU
sa32006	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa42459	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa42460	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa42461	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH elna HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
autosomal dominant cutis laxa 1	Cutis laxa, autosomal dominant	123700
supravalvular aortic stenosis	Supravalvar aortic stenosis	185500

DISEASE ASSOCIATED WITH elna VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	biological_process (more)
Cellular Component	collagen-containing extracellular matrix (more)
Molecular Function	extracellular matrix structural constituent (more)

GO Terms (all 3)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR003979 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	elna-001 (1)	4031	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIES

Ab1-elna (1)

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM elna No data available

MARKER RELATIONSHIPS

elnaContained in:

[BAC] CH73-156F22 (1) (order this), CH211-257O19 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001080063 (1)	3599bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX640522 (1)	154564bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q0Q5Z1 (1)	1164aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:72306 (1)

Sequence Information (all 173)

OTHER elna GENE PAGES

Alliance (1)

Gene:790915 (1)

VEGA:OTTDARG00000027877 (1)

VEGA:OTTDARG00000039644 (1)

ORTHOLOGY for elna (Chr: 15)

CITATIONS (17)

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