Gene

elna

ID

ZDB-GENE-061212-1

Name

elastin a

Symbol

elna Nomenclature History

Previous Names

eln1 (1)
tropoelastin (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have extracellular matrix structural constituent. Predicted to localize to collagen-containing extracellular matrix. Is expressed in cranium; heart; nervous system; swim bladder; and ventral aorta. Human ortholog(s) of this gene implicated in several diseases, including aortic disease (multiple); autoimmune disease of musculoskeletal system (multiple); cutis laxa (multiple); retinal disease (multiple); and vasculitis (multiple). Orthologous to human ELN (elastin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 5 publications

Cross-Species Comparison

Alliance

High Throughput Data

Expression Atlas

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With elna Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal dominant cutis laxa 1	Alliance	Cutis laxa, autosomal dominant	123700
supravalvular aortic stenosis	Alliance	Supravalvar aortic stenosis	185500

Associated With elna Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR003979	Tropoelastin

Domain Details Per Protein

Protein	Length	Tropoelastin
UniProtKB:A0A8M6YSC6 InterPro	1210
UniProtKB:A0A8M6Z1D8 InterPro	1198
UniProtKB:A0A8M6YSD1 InterPro	1197
UniProtKB:A0A8N1TQS2 InterPro	1164
UniProtKB:A0A8M9Q0K7 InterPro	1198
UniProtKB:A0A8M6YUV6 InterPro	1119
UniProtKB:A0A8M6Z0Q8 InterPro	1208
UniProtKB:A0A8M6YSD6 InterPro	1119
UniProtKB:A0A8M6YT25 InterPro	1212
UniProtKB:A0A8M3AGY9 InterPro	1149
UniProtKB:A0A8M6YT42 InterPro	1016
UniProtKB:A0A8M6YUV1 InterPro	1204
UniProtKB:A0A8M9QC60 InterPro	1073
UniProtKB:A0A8M6YUU6 InterPro	1210
UniProtKB:A0A8M9QHD9 InterPro	1002
UniProtKB:A0A8M6YT31 InterPro	1207
UniProtKB:A0A8M6Z1D3 InterPro	1210
UniProtKB:A0A8M6Z0R1 InterPro	1169
UniProtKB:A0A8M6YT37 InterPro	1162

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-elna	polyclonal	elna	IgG	Rabbit	IHC		4

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations