Gene

elna

ID

ZDB-GENE-061212-1

Name

elastin a

Symbol

elna Nomenclature History

Previous Names

eln1 (1)
tropoelastin (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have extracellular matrix structural constituent. Predicted to localize to collagen-containing extracellular matrix. Is expressed in cranium; heart; nervous system; swim bladder; and ventral aorta. Human ortholog(s) of this gene implicated in several diseases, including aortic disease (multiple); autoimmune disease of musculoskeletal system (multiple); cutis laxa (multiple); retinal disease (multiple); and vasculitis (multiple). Orthologous to human ELN (elastin).

Genome Resources

Note

None

Expression

All Expression Data

11 figures from 3 publications

Cross-Species Comparison

Alliance

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With elna Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal dominant cutis laxa 1	Alliance	Cutis laxa, autosomal dominant	123700
supravalvular aortic stenosis	Alliance	Supravalvar aortic stenosis	185500

Associated With elna Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR003979	Tropoelastin

Domain Details Per Protein

Protein	Length	Tropoelastin
UniProtKB:A0A2R4FXL9 InterPro	267
UniProtKB:A0A2R4FXL7 InterPro	194
UniProtKB:A0A2R4FXJ8 InterPro	387
UniProtKB:Q0Q5Z1 InterPro	1164
UniProtKB:A0A2R4FXP6 InterPro	194
UniProtKB:A0A2R4FXM5 InterPro	179
UniProtKB:A0A2R4FXL8 InterPro	168
UniProtKB:A0A2R4FXM3 InterPro	179
UniProtKB:A0A2R4FXM6 InterPro	194
UniProtKB:A0A2R4FXL6 InterPro	128
UniProtKB:A0A2R4FXJ9 InterPro	148
UniProtKB:A0A2R4FXN8 InterPro	273
UniProtKB:A0A2R4FXJ1 InterPro	457
UniProtKB:A0A2R4FXJ2 InterPro	211
UniProtKB:A0A2R4FXP2 InterPro	73
UniProtKB:A0A2R4FXK0 InterPro	126
UniProtKB:A0A2R4FXN6 InterPro	136
UniProtKB:A0A2R4FXN2 InterPro	179
UniProtKB:A0A2R4FXP3 InterPro	275
UniProtKB:A0A2R4FXK8 InterPro	104
UniProtKB:A0A2R4FXK7 InterPro	446
UniProtKB:A0A2R4FXL2 InterPro	257
UniProtKB:A0A2R4FXN3 InterPro	265
UniProtKB:A0A2R4FXK3 InterPro	264
UniProtKB:A0A2R4FXN0 InterPro	277
UniProtKB:A0A2R4FXN4 InterPro	360
UniProtKB:A0A2R4FXH6 InterPro	265
UniProtKB:A0A2R4FXM0 InterPro	360
UniProtKB:A0A2R4FXM8 InterPro	360
UniProtKB:A0A2R4FXK1 InterPro	104
UniProtKB:A0A2R4FXJ7 InterPro	260
UniProtKB:A0A2R4FXM7 InterPro	287
UniProtKB:A0A2R4FXL3 InterPro	324
UniProtKB:A0A2R4FXM1 InterPro	128

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-elna	polyclonal	elna	IgG	Rabbit	IHC		4

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Citations