ZFIN ID: ZDB-GENE-061212-1
Gene Name: elastin a
Gene Symbol: elna    Nomenclature History

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Previous Names: eln1 (1), tropoelastin (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have extracellular matrix structural constituent. Predicted to localize to collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in several diseases, including aortic disease (multiple); cutis laxa (multiple); retinal disease (multiple); rheumatic disease (multiple); and vasculitis (multiple). Is expressed in cranium; heart; nervous system; swim bladder; and ventral aorta. Orthologous to human ELN (elastin).
Genome Resources: Alliance (1),  Gene:790915 (1), 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH elna HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant cutis laxa 1 Alliance Cutis laxa, autosomal dominant 123700
supravalvular aortic stenosis Alliance Supravalvar aortic stenosis 185500
DISEASE ASSOCIATED WITH elna VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process biological_process (more)
Cellular Component collagen-containing extracellular matrix (more)
Molecular Function extracellular matrix structural constituent (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA elna-001 (1) 4031
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-elna polyclonal IgG Rabbit IHC 2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM elna No data available
MARKER RELATIONSHIPS
elna Contained in: [BAC] CH73-156F22 (1), CH211-257O19 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001080063 (1) 3599 nt
Genomic GenBank:BX640522 (1) 154564 nt
Select Tool
Polypeptide UniProtKB:Q0Q5Z1 (1) 1164 aa
Sequence Information (all 172)
ORTHOLOGY for elna ( Chr: 15 )
CITATIONS (17)