Gene
bcl11ba
- ID
- ZDB-GENE-061207-62
- Name
- BCL11 transcription factor B a
- Symbol
- bcl11ba Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in thymus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human BCL11B (BAF chromatin remodeling complex subunit BCL11B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 49 | Alliance | Immunodeficiency 49, severe combined | 617237 |
| Intellectual developmental disorder with dysmorphic facies, speech delay, and T-cell abnormalities | 618092 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|
|
UniProtKB:F1QPF5
|
151 | ||
|
UniProtKB:B8JHY1
|
208 | ||
|
UniProtKB:A5PLI2
|
208 | ||
|
UniProtKB:A0A2R8Q8A6
|
814 | ||
|
UniProtKB:X1WBZ3
|
776 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
bcl11ba-202
(1)
|
1065 nt | |
| mRNA |
bcl11ba-203
(1)
|
3240 nt | |
| ncRNA |
bcl11ba-003
(1)
|
543 nt |
Interactions and Pathways
No data available
Plasmids
No data available