header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-061207-62
Gene Name: BAF chromatin remodeling complex subunit BCL11B a
Gene Symbol: bcl11ba    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: bcl11b.1 (1), bcl11b, si:dkey-238i13.1, wu:fj43a03, zgc:165628 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in thymus. Orthologous to human BCL11B (BAF chromatin remodeling complex subunit BCL11B).
Genome Resources: Alliance (1),  Gene:100093707 (1),  Ensembl(GRCz11):ENSDARG00000062510 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019962Tg Transgenic Insertion Unknown Unknown DNA
la027819Tg Transgenic Insertion Unknown Unknown DNA
sa2902 Point Mutation Unknown Premature Stop ENU
sa6468 Point Mutation Unknown Premature Stop ENU
sa16831 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23039 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36375 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-bcl11ba N/A 1
    MO2-bcl11ba N/A 1
    DISEASE ASSOCIATED WITH bcl11ba HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Immunodeficiency 49 617237
    Intellectual developmental disorder with dysmorphic facies, speech delay, and T-cell abnormalities 618092
    DISEASE ASSOCIATED WITH bcl11ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013087 (1)
  • InterPro:IPR036236 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • Pfam:PF00096 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bcl11ba-202 (1)    Ensembl 1065
    bcl11ba-203 (1)    Ensembl 3240
    ncRNA bcl11ba-003 (1) 543
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bcl11ba No data available
    MARKER RELATIONSHIPS
    bcl11ba Contained in: [BAC] CH211-262A18 (1) (order this), DKEY-238I13 (1) (order this)
    bcl11ba Encodes: [EST] fj43a03
    [cDNA] MGC:165628 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001099260 (1) 1087 bp
    Genomic GenBank:CR382377 (1) 105441 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q8A6 (1) 814 aa
    Sequence Clusters UniGene:144475 (1)
    Sequence Information (all 24)
    ORTHOLOGY for bcl11ba ( Chr: 17 )
    CITATIONS (30)