Gene

sept15

ID
ZDB-GENE-061103-265
Name
septin 15
Symbol
sept15 Nomenclature History
Previous Names
  • sept7b
  • fc18f05
  • fc92f03
  • wu:fb19h03
  • wu:fc18f05
  • wu:fc92f03
  • zgc:153214 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have GTPase activity and molecular adaptor activity. Involved in several processes, including cardiac muscle contraction; organelle assembly; and pronephros morphogenesis. Predicted to localize to cell division site and cytoskeleton. Is expressed in several structures, including digestive system; heart; hypoblast; nervous system; and pronephros. Orthologous to human SEPTIN7 (septin 7).
Genome Resources
Note
The original name assignment (sept7b) was based on AA similarity alone. Newer genome information and synteny data suggests that this gene, while orthologous to SEPT7 genes, is not the paralog of sept7a and must there be renamed.
Comparative Information
Expression
All Expression Data
11 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
19 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sept15 Human Ortholog
No data available
Associated With sept15 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR030379 Septin-type guanine nucleotide-binding (G) domain
Family IPR008115 Septin 7
Family IPR016491 Septin
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Septin Septin 7 Septin-type guanine nucleotide-binding (G) domain
UniProtKB:A0JMF4 429
UniProtKB:A0A0R4IN26 428
UniProtKB:A0A0R4IPW8 265
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-sept7 polyclonal IgG Rabbit
  • IHC
  • WB
Santa Cruz Biotechnology, Inc.
4
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations