Gene

ap1b1

ID
ZDB-GENE-061025-1
Name
adaptor related protein complex 1 subunit beta 1
Symbol
ap1b1 Nomenclature History
Previous Names
  • skb (1)
  • fa11e04
  • si:ch211-149d1.1
  • skylab (1)
  • wu:fa11e04
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have clathrin binding activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception; regulation of sodium ion transmembrane transporter activity; and sensory organ development. Predicted to localize to clathrin adaptor complex. Is expressed in brain; eye; female organism; inner ear; and otic vesicle. Orthologous to human AP1B1 (adaptor related protein complex 1 subunit beta 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ap1b1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Keratitis-ichthyosis-deafness syndrome, autosomal recessive 242150
Associated With ap1b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
Domain IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
Domain IPR015151 Beta-adaptin appendage, C-terminal subdomain
Family IPR016342 AP-1/2/4 complex subunit beta
Family IPR026739 AP complex subunit beta
Homologous_superfamily IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomain
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR012295 TBP domain superfamily
Homologous_superfamily IPR013037 Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain
Homologous_superfamily IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Repeat IPR000225 Armadillo
Domain Details Per Protein
Protein Length AP-1/2/4 complex subunit beta AP complex subunit beta Armadillo Armadillo-like helical Armadillo-type fold Beta-adaptin appendage, C-terminal subdomain Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain Clathrin adaptor, appendage, Ig-like subdomain superfamily Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain Clathrin/coatomer adaptor, adaptin-like, N-terminal Coatomer/calthrin adaptor appendage, C-terminal subdomain TBP domain superfamily
UniProtKB:A5PMT0 124
UniProtKB:A0A2R8Q6M9 976
UniProtKB:A0A2R8QRX3 952
UniProtKB:A5PMS9 947
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations