Gene

ap1b1

ID
ZDB-GENE-061025-1
Name
adaptor related protein complex 1 subunit beta 1
Symbol
ap1b1 Nomenclature History
Previous Names
  • skb (1)
  • fa11e04
  • si:ch211-149d1.1
  • skylab (1)
  • wu:fa11e04
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have clathrin binding activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception; hair cell differentiation; and sensory organ development. Predicted to localize to clathrin adaptor complex. Is expressed in brain; eye; female organism; inner ear; and otic vesicle. Orthologous to human AP1B1 (adaptor related protein complex 1 subunit beta 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ap1b1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Keratitis-ichthyosis-deafness syndrome, autosomal recessive 242150
Associated With ap1b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
Domain IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
Domain IPR015151 Beta-adaptin appendage, C-terminal subdomain
Family IPR016342 AP-1/2/4 complex subunit beta
Family IPR026739 AP complex subunit beta
Homologous_superfamily IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomain
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR012295 TBP domain superfamily
Homologous_superfamily IPR013037 Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain
Homologous_superfamily IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Repeat IPR000225 Armadillo
Domain Details Per Protein
Protein Length AP-1/2/4 complex subunit beta AP complex subunit beta Armadillo Armadillo-like helical Armadillo-type fold Beta-adaptin appendage, C-terminal subdomain Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain Clathrin adaptor, appendage, Ig-like subdomain superfamily Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain Clathrin/coatomer adaptor, adaptin-like, N-terminal Coatomer/calthrin adaptor appendage, C-terminal subdomain TBP domain superfamily
UniProtKB:A5PMT0 124
UniProtKB:A0A2R8Q6M9 976
UniProtKB:A5PMS9 947
UniProtKB:A0A2R8QRX3 952
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations