ZFIN ID: ZDB-GENE-061013-96
Gene Name: phosphatidylinositol 4-kinase, catalytic, beta
Gene Symbol: pi4kb    Nomenclature History

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Previous Names: pik4cb (1), PI4KIII-beta (1), zgc:152715 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have 1-phosphatidylinositol 4-kinase activity. Involved in semicircular canal development. Predicted to localize to cytoplasm and membrane. Is expressed in brain; head; pharyngeal arch 3-7; and semicircular canal. Orthologous to human PI4KB (phosphatidylinositol 4-kinase beta).
Genome Resources: Alliance (1),  Gene:563201 (1),  Ensembl(GRCz11):ENSDARG00000040111 (1)
GENE EXPRESSION
All Expression Data: 3 figures from Petko et al., 2009
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
gyf1 Small Deletion Unknown Unknown CRISPR
gyf2 Small Deletion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-pi4kb 1
MO1-pi4kb N/A 1
MO2-pi4kb N/A 1
DISEASE ASSOCIATED WITH pi4kb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH pi4kb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process semicircular canal development (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function 1-phosphatidylinositol 4-kinase activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pi4kb-201 (1)    Ensembl 4300
pi4kb-202 (1)    Ensembl 614
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pi4kb No data available
MARKER RELATIONSHIPS
pi4kb Contained in: [BAC] DKEY-23O4 (1) (order this)
pi4kb Encodes: [cDNA] MGC:152715 (1), MGC:198343 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001034977 (1) 3570 nt
Genomic GenBank:BX005412 (1) 250962 nt Blast at MegaBLAST
Polypeptide UniProtKB:B7ZVK4 (1) 850 aa
Sequence Information (all 24)
ORTHOLOGY for pi4kb ( Chr: 16 )
CITATIONS (23)